THE EFFECTS OF KOREAN RED GINSENG ON HEME OXYGENASE-1 WITH A FOCUS ON MITOCHONDRIAL FUNCTION IN PATHOPHYSIOLOGIC CONDITIONS

Korean Red Ginseng (KRG) plays a key role in heme oxygenase (HO)-1 induction under physical and moderate oxidative stress conditions.The transient and mild induction of HO-1 is beneficial for cell protection, mitochondrial function, regeneration, and intercellular communication.However, chronic HO-1 overexpression is detrimental in severely injured

Alaa Elmazny, Sherif M Hamdy, Maged Abdel-Naseer, Nevin M Shalaby, Hatem S Shehata, Nirmeen A Kishk, Mona A Nada, Husam S Mourad, Mohamed I Hegazy, Ahmed Abdelalim, Sandra M Ahmed, Ghada Hatem, Amr M Fouad, Hadel Mahmoud, Amr Hassan Neurology Department, Faculty of Medicine, Cairo University, Cairo, EgyptCorrespondence: Hatem S ShehataNeurology Dep